Simvastatin belongs to the group of medications known as HMG CoA reductase inhibitors ("statins"). We do not want anyone to go from the frying pan into the fire.How does this medication work? What will it do for me? And one more thing…no one should stop a statin without consulting the prescriber. Thanks for letting us know about your experience. Please let us know how you or someone you love has fared on a statin-type drug. We don’t know what the true incidence of some of the so-called minor side effects really is. And many individuals never suffer any side effects. Those who have had one heart attack can reduce the risk of a second by taking a statin. The data suggest that people who have clearly diagnosed heart disease can benefit. We recognize that some people really do need these medications to prevent a heart attack or a stroke. What about arthritis, nerve pain or peripheral neuropathy? Again we are clueless. How common are sexual problems with statins? No one really knows. Until recently the FDA assumed that memory problems and blood sugar elevation were so rare as to be almost forgettable. What we do not know is how common some of these side effects may be. Digestive upset, nausea, constipation, diarrhea, flatulence.Nerve pain, peripheral neuropathy, leg cramps.Memory problems, cognitive dysfunction, confusion, amnesia.Muscle pain or spasms (any where in the body, including legs, shoulders, back, arms or neck).Potential adverse reactions patients and their families should be aware of include: Simcor (simvastatin/niacin extended-release).Products containing statins in combination with other drugs include:Īdvicor (lovastatin/niacin extended-release).Why did it take the FDA so long to figure this out? What other side effects should we be paying more attention to when it comes to statin-type drugs: A husband and wife taking Lipitor had increasing trouble controlling their glucose levels. The first case came to our attention almost ten years ago. We have heard from many people who have had significant problems with blood sugar control while taking a statin-type drug. Not a good thing for the public health and certainly not good for the individual affected with a new serious chronic illness.”Īmidst the statistics we tend to forget that individuals are affected. That would equate to 100,000 new statin-induced diabetics. “More than 20 million Americans take statins. Topol, the stronger the statin and the higher the dose the greater the likelihood of diabetes. With this data manipulation the FDA diluted the impact of potent statins on blood sugar increases. The FDA lumped relatively “weak” statins together with more potent statins like atorvastatin ( Lipitor), rosuvastatin ( Crestor) and simvastatin ( Zocor).
Topol points out that the way the data were analyzed could be misleading. In an op-ed article published in the New York Times (March 4, 2012) titled, “The Diabetic Dilemma for Statin Users,” Dr. He is one of the country’s leading cardiologists. We are not so sure this is such a “small increased risk.” Eric Topol, MD, seems to agree with us. “A small increased risk of raised blood sugar levels and the development of Type 2 diabetes have been reported with the use of statins.” The FDA has worded its warning cautiously: The last thing they need is to have their blood sugar go up, since that can increase the risk of the very complications people are trying to avoid (heart attacks and strokes, not to mention kidney damage, nerve pain and eye problems). Millions of people with elevated cholesterol are trying desperately to reduce their likelihood of having a heart attack or a stroke. The Food and Drug Administration upset the applecart when it announced that statin-type cholesterol-lowering medications like simvastatin ( Zocor) could raise blood sugar levels and increase the risk for diabetes.